Name: Ipamorelin — 5mg Research Peptide
Brand: Optimus Peptides
Availability: OutOfStock

RESEARCH USE ONLY - Not for human or veterinary use. Supplied for lawful in vitro research and qualified laboratory investigation only. QUALITY - Peptide catalogue items are specified at ≥99% purity with batch documentation. Store lyophilised powders as directed before reconstitution. COMPLIANCE - You are responsible for lawful purchase, possession, and use in your jurisdiction, including institutional and safety requirements. SAFE HANDLING - Use trained personnel, appropriate PPE, and aseptic technique. Do not ingest, inject, or use outside a controlled research setting. POLICIES & ORDERS - Shipping, returns, and research-use terms apply to every order. Read our Research Use Policy and footer legal links before buying.

What is Ipamorelin?

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that acts as an agonist at the ghrelin receptor (GHS-R1a) on pituitary somatotrophs. Unlike earlier GHRP generations, Ipamorelin was designed for high selectivity: in many preclinical models it stimulates GH release with comparatively modest effects on cortisol, prolactin, and adrenocorticotropic hormone when dosed within studied ranges.

Because of its clean pharmacological profile, Ipamorelin is frequently used as a reference ligand when ranking other secretagogues, testing receptor mutants, or exploring pulsatile GH dynamics in perfused pituitary systems. Optimus Peptides supplies Ipamorelin exclusively for lawful research - not for athletic, cosmetic, or clinical use outside approved studies.

Product Code

Ipamorelin

Target

GHS-R1a (ghrelin receptor)

Class

Pentapeptide secretagogue

Approx. Molecular Mass

~712 Da

Presentation

5mg lyophilised vial

Research Background

The ghrelin receptor is a Gq/11-coupled GPCR that triggers GH secretion when activated in somatotrophs. Ipamorelin literature highlights:

GH release in rats and swine with dose-dependent, bell-shaped response curves typical of secretagogues.
Favourable selectivity versus cortisol and prolactin compared with older GHRP peptides in several animal studies.
Use as a pharmacological probe in binding assays, β-arrestin recruitment screens, and biased-signalling investigations.
Combination protocols with GHRH analogues (e.g. CJC-1295 or tesamorelin classes) to study synergistic GH pulsatility.

Research Applications

In-vitro pituitary cell GH secretion assays with defined controls
Structure–activity studies on ghrelin-mimetic scaffolds
Metabolic and appetite-regulation models where ghrelin signalling is manipulated

Technical Specifications

Appearance

White lyophilised powder

Purity

≥99% (HPLC specification)

Format

Lyophilised (freeze-dried)

Net Mass

5mg peptide per vial (label)

Reconstitution

Bacteriostatic or sterile water per protocol

Storage (Lyophilised)

−20°C, desiccated, protect from light

Storage (Reconstituted)

2–8°C; aliquot to limit oxidation

Shelf Life

Refer to batch label (lyophilised)

CoA

Available on request per batch

Frequently Asked Questions

Is Ipamorelin “safer” than other GHRPs?

Published animal data suggest a cleaner endocrine profile at some doses, but no general safety claim can be made for research material outside a controlled protocol. Always follow dose–response characterisation in your own system.

Can I use it for muscle building in humans?

No. This product is not for human consumption or performance enhancement. Sale and possession may be restricted in your jurisdiction.

Does Ipamorelin replace GHRH analogues?

It works through a different receptor class. Many studies pair secretagogues with GHRH analogues to probe axis integration; they are complementary tools, not interchangeable.

When will stock return?

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Ipamorelin — GH Secretagogue