RESEARCH USE ONLY - Not for human or veterinary use. Supplied for lawful in vitro research and qualified laboratory investigation only. QUALITY - Peptide catalogue items are specified at ≥99% purity with batch documentation. Store lyophilised powders as directed before reconstitution. COMPLIANCE - You are responsible for lawful purchase, possession, and use in your jurisdiction, including institutional and safety requirements. SAFE HANDLING - Use trained personnel, appropriate PPE, and aseptic technique. Do not ingest, inject, or use outside a controlled research setting. POLICIES & ORDERS - Shipping, returns, and research-use terms apply to every order. Read our Shipping Policy, Returns Policy, and Research Use Policy before buying.

MOTS-c 10mg lyophilised vial - for research purposes only

Purity

≥99%

Format

Lyophilised

Size

10mg

Storage

−20°C

Out of stock

Mitochondrial-derived · Metabolic peptide

MOTS-c — Mitochondrial-Derived Peptide

Mitochondrial open reading frame peptide · 10mg lyophilised

≥99% Purity

CoA on release

MOTS-c is a 16-amino-acid mitochondrial-derived peptide studied for AMPK activation, glucose handling, and exercise-mimetic phenotypes in preclinical metabolic models. Research use only.

This SKU is currently unavailable.

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What is MOTS-c?

MOTS-c is a mitochondrial-derived peptide (MDP) encoded within the mitochondrial 12S rRNA gene, studied as a bioactive signal regulating nuclear transcription and systemic metabolism.

Preclinical work links MOTS-c to AMPK pathway activation, improved glucose uptake, and resistance to high-fat-diet phenotypes in rodent models.

Supplied for lawful laboratory research only — not for human performance enhancement or clinical use.

Product Code

MOTS-c

Class

Mitochondrial-derived peptide

Length

16 amino acids

Presentation

10mg lyophilised vial

Research Background

AMPK and AKT phosphorylation readouts in myotubes and adipocytes.
Glucose tolerance assays in diet-induced obesity rodent models.
Transcriptomic profiling of antioxidant and one-carbon metabolism genes.
Comparative studies with NAD⁺ pathway modulators.

Research Applications

Insulin resistance and mitochondrial stress cell models
Mitonuclear signalling mechanism studies
Pairing with NAD⁺ in ageing pathway screens

Technical Specifications

Appearance

White lyophilised powder

Purity

≥99% (HPLC specification)

Format

Lyophilised (freeze-dried)

Net Mass

10mg peptide per vial (label)

Reconstitution

Bacteriostatic or sterile water per protocol

Storage (Lyophilised)

−20°C, desiccated, protect from light

Storage (Reconstituted)

2–8°C; aliquot to limit degradation

Shelf Life

Refer to batch label (lyophilised)

CoA

Available on request per batch

Frequently Asked Questions

Is MOTS-c for human mitochondrial “boosting”?

No. Sold strictly for qualified in-vitro and lawful animal research.

How does MOTS-c relate to NAD+?

Both are studied in bioenergetics and ageing biology; many labs run parallel pathway arms.

When will stock return?

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