RESEARCH USE ONLY - Not for human or veterinary use. Supplied for lawful in vitro research and qualified laboratory investigation only. QUALITY - Peptide catalogue items are specified at ≥99% purity with batch documentation. Store lyophilised powders as directed before reconstitution. COMPLIANCE - You are responsible for lawful purchase, possession, and use in your jurisdiction, including institutional and safety requirements. SAFE HANDLING - Use trained personnel, appropriate PPE, and aseptic technique. Do not ingest, inject, or use outside a controlled research setting. POLICIES & ORDERS - Shipping, returns, and research-use terms apply to every order. Read our Shipping Policy, Returns Policy, and Research Use Policy before buying.
NAD+ lyophilised vial - for research purposes only
Purity
≥99%
Format
Lyophilised
Size
500mg
Storage
−20°C
Out of stock
Coenzyme · Redox · Cellular energy

NAD+ — Nicotinamide Adenine Dinucleotide

Oxidised dinucleotide coenzyme · 500mg lyophilised

≥99% Purity
CoA on release

NAD+ is the oxidised form of nicotinamide adenine dinucleotide, a ubiquitous coenzyme in redox biochemistry. Laboratories use high-purity NAD+ to study sirtuin activity, PARP-dependent DNA repair readouts, mitochondrial respiration assays, and NAD salvage-pathway pharmacology — research use only.

This SKU is currently unavailable.

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What is NAD+?

Nicotinamide adenine dinucleotide (NAD+) is a dinucleotide coenzyme composed of two nucleotides joined through their phosphate groups. In its oxidised form it accepts hydride equivalents during catabolic metabolism and serves as an essential electron carrier linking glycolysis, the TCA cycle, and oxidative phosphorylation.

Beyond classical bioenergetics, NAD+ is a substrate for enzymes including sirtuins (SIRT1–7), poly(ADP-ribose) polymerases (PARPs), and CD38/BST1 ectoenzymes that regulate DNA repair, chromatin remodelling, and immune-cell metabolism.

Optimus Peptides supplies lyophilised NAD+ exclusively for lawful laboratory research — not for human or veterinary use, and not as a dietary supplement.

Product Code
NAD+
Chemical Class
Pyridine nucleotide coenzyme
Approx. Molecular Mass
~663 Da
Presentation
500mg lyophilised vial

Research Background

NAD+ biology spans enzymology and systems-level metabolism research. Common themes include:

  • Quantifying NAD+/NADH ratios in cells and organoids using enzymatic cycling or LC-MS.
  • Probing sirtuin activity after controlled NAD+ repletion or depletion.
  • PARP activation models where NAD+ consumption links genotoxic stress to energetic collapse.
  • Mitochondrial stress tests where extracellular NAD+ modulates respiration readouts.
  • Comparative studies with NAD+ precursors (NMN, NR) versus direct coenzyme delivery.

Research Applications

  • Cell-culture supplementation for redox and ageing pathway screens
  • Enzyme kinetic assays requiring defined cofactor concentrations
  • Pairing with mitochondrial-derived peptides such as MOTS-c in metabolic models

Technical Specifications

Appearance
White to off-white lyophilised powder
Purity
≥99% (HPLC specification)
Format
Lyophilised (freeze-dried)
Net Mass
500mg per vial (label)
Reconstitution
Sterile water or buffer per protocol; protect from light
Storage (Lyophilised)
−20°C, desiccated, protect from light
Storage (Reconstituted)
2–8°C; use within protocol-defined window
Shelf Life
Refer to batch label (lyophilised)
CoA
Available on request per batch

Frequently Asked Questions

How is NAD+ different from NMN or NR?

NMN and NR are precursors converted through the salvage pathway. This product is the coenzyme itself for direct addition protocols.

Is NAD+ the same as retail “NAD boosters”?

No. Our material is sold strictly for qualified laboratory research.

When will stock return?

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