RESEARCH USE ONLY - Not for human or veterinary use. Supplied for lawful in vitro research and qualified laboratory investigation only.·QUALITY - Peptide catalogue items are specified at ≥99% purity with batch documentation. Store lyophilised powders as directed before reconstitution.·COMPLIANCE - You are responsible for lawful purchase, possession, and use in your jurisdiction, including institutional and safety requirements.·SAFE HANDLING - Use trained personnel, appropriate PPE, and aseptic technique. Do not ingest, inject, or use outside a controlled research setting.·POLICIES & ORDERS - Shipping, returns, and research-use terms apply to every order. Read our Research Use Policy and footer legal links before buying.·
TB-500 refers to a short synthetic fragment related to Thymosin Beta-4, studied in models of cell migration, wound closure, and tissue remodelling. Supplied for laboratory research only.
Size - 5mg
Supplied as 5mg lyophilised peptide per vial (single presentation).
In research supply catalogues, TB-500 refers to a synthetic peptide fragment whose design is derived from the biologically active region of Thymosin Beta-4 (Tβ4), a 43-amino-acid actin-binding protein involved in cytoskeletal organisation and cell motility. The parent protein is conserved across species and is well characterised in wound-repair and inflammation literature.
The TB-500 designation is used by laboratories to study cell migration, angiogenesis readouts, and matrix remodelling in controlled systems - typically alongside other regenerative tools such as BPC-157 or matrix assays. Optimus Peptides supplies this material only for lawful research; it is not a medicine and not for human or veterinary administration.
Each vial contains lyophilised powder intended for reconstitution with an appropriate sterile or preserved diluent (see bacteriostatic water) under aseptic technique.
Product Code
TB-500
Class
Tβ4-related synthetic fragment
Presentation
5mg lyophilised vial
Mechanistic Theme
Actin · migration · repair models
Research Background
Preclinical work on Tβ4 and related fragments spans cardiovascular, dermal, ophthalmic, and musculoskeletal models. Recurring mechanistic threads include:
Regulation of G-actin / F-actin dynamics and lamellipodia formation in migrating cells.
Up-regulation or coordination of growth-factor and cytokine networks during tissue repair windows.
Angiogenesis-associated readouts in wound and ischaemia surrogates (model-dependent).
Cardiac and neural injury models where cell survival and remodelling endpoints are scored.
Research Applications
Investigators order TB-500-class peptides for studies such as:
Scratch-wound, transwell migration, and 3D spheroid motility assays
Corneal, dermal, and surgical wound–closure time-course models in animals
Comparative efficacy versus BPC-157 or other regenerative candidates in the same cohort
Published outcomes vary by species, dose route, and readout. Optimus Peptides makes no efficacy or safety claims outside a compliant research programme.
Technical Specifications
Appearance
White lyophilised powder
Purity
≥99% (HPLC specification)
Format
Lyophilised (freeze-dried)
Net Mass
5mg peptide per vial (label)
Reconstitution
Sterile or bacteriostatic water per protocol
Storage (Lyophilised)
−20°C, desiccated, protect from light
Storage (Reconstituted)
2–8°C; avoid repeated freeze–thaw
Shelf Life
24 months (lyophilised, unopened - refer to batch label)
CoA
Available on request per batch
Frequently Asked Questions
Is TB-500 available to order?
Yes — 5mg lyophilised vials are in stock at each. Add to cart from this page. If a batch sells through, the catalogue may show a notify option again.
Is TB-500 the same as full-length Thymosin Beta-4?
No. TB-500 is a research fragment / analogue inspired by the active region of Tβ4, not the full 43-mer native protein. Always confirm identity and sequence on your batch CoA.
What diluent should I use?
For multidose aliquoting after reconstitution, many labs use bacteriostatic water. For single-use experiments, sterile water for injection may be appropriate. Match the diluent to your validated method.
Can I use this in humans or animals outside an approved study?
No. Purchase and use must comply with all applicable laws and institutional requirements. This product is labelled and sold for research only.
